Weiwei Guo Selected Research

Waardenburg Syndrome (Klein Syndrome)

6/2021	CRISPR/Cas9-mediated correction of MITF homozygous point mutation in a Waardenburg syndrome 2A pig model.
11/2017	Creation of miniature pig model of human Waardenburg syndrome type 2A by ENU mutagenesis.
1/2016	A de novo silencer causes elimination of MITF-M expression and profound hearing loss in pigs.

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Weiwei Guo Research Topics

Disease

20	Neoplasms (Cancer) 10/2022 - 07/2010
10	Hearing Loss (Hearing Impairment) 06/2021 - 08/2002
6	Breast Neoplasms (Breast Cancer) 01/2021 - 05/2011
4	Inflammation (Inflammations) 06/2021 - 01/2017
4	Infections 01/2021 - 12/2015
3	COVID-19 08/2022 - 01/2021
3	Waardenburg Syndrome (Klein Syndrome) 06/2021 - 01/2016
3	Noise-Induced Hearing Loss (Acoustic Trauma) 06/2021 - 01/2014
3	Carcinogenesis 10/2020 - 05/2015
3	Stomach Neoplasms (Stomach Cancer) 08/2019 - 05/2015
2	Sensorineural Hearing Loss 01/2022 - 12/2015
2	Necrosis 04/2021 - 12/2017
2	Hypertrophy 01/2021 - 01/2018
2	Body Weight (Weight, Body) 11/2020 - 01/2018
2	Ovarian Neoplasms (Ovarian Cancer) 10/2020 - 01/2020
2	Wounds and Injuries (Trauma) 08/2017 - 01/2014
2	Xeroderma Pigmentosum (Kaposi's Disease) 01/2017 - 08/2015
2	Deafness (Deaf Mutism) 01/2016 - 05/2006
2	Hypoxia (Hypoxemia) 05/2015 - 03/2004
2	Hepatocellular Carcinoma (Hepatoma) 05/2014 - 01/2014
1	Congenital Abnormalities (Deformity) 01/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 07/2021
1	Melanoma (Melanoma, Malignant) 07/2021
1	Memory Disorders (Memory Loss) 04/2021
1	Acute Lung Injury 03/2021
1	Pneumonia (Pneumonitis) 03/2021
1	Pulmonary Edema 03/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Thrombosis (Thrombus) 01/2021
1	Severe Acute Respiratory Syndrome 01/2021
1	Autistic Disorder (Autism) 11/2020
1	Dysbiosis 11/2020
1	Mood Disorders (Mood Disorder) 11/2020
1	Genomic Instability 01/2020
1	Proctitis 08/2019
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 08/2019
1	Non-alcoholic Fatty Liver Disease 02/2018

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 08/2022 - 10/2011
4	Peptides (Polypeptides)IBA 01/2021 - 10/2017
4	Pharmaceutical PreparationsIBA 02/2018 - 05/2011
3	DNA (Deoxyribonucleic Acid)IBA 06/2021 - 01/2017
3	InflammasomesIBA 06/2021 - 12/2015
3	AntigensIBA 01/2021 - 03/2020
3	Long Noncoding RNAIBA 01/2021 - 01/2018
2	VaccinesIBA 08/2022 - 09/2021
2	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2021 - 01/2021
2	RNA (Ribonucleic Acid)IBA 10/2020 - 01/2020
2	HLA-A2 Antigen (HLA A2 Antigen)IBA 10/2020 - 03/2020
2	Messenger RNA (mRNA)IBA 01/2020 - 05/2015
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2017 - 05/2011
2	Hydroxyl RadicalIBA 01/2014 - 07/2013
1	Interleukin-4 (Interleukin 4)IBA 10/2022
1	Polysaccharides (Glycans)IBA 10/2022
1	PlasticsIBA 01/2022
1	Subunit VaccinesIBA 09/2021
1	OligodeoxyribonucleotidesIBA 06/2021
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 06/2021
1	oridoninIBA 06/2021
1	Saline SolutionIBA 04/2021
1	Autophagy-Related ProteinsIBA 04/2021
1	AluminumIBA 04/2021
1	Beclin-1IBA 04/2021
1	CytokinesIBA 03/2021
1	ProgranulinsIBA 03/2021
1	ebosinIBA 01/2021
1	JMB2002IBA 01/2021
1	1,2-distearoylphosphatidylethanolamine (DSPE)IBA 01/2021
1	Imiquimod (Aldara)FDA LinkGeneric 01/2021
1	EnzymesIBA 01/2021
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2021
1	LuciferasesIBA 01/2021
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2021
1	Interleukin-17 (Interleukin 17)IBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	GasotransmittersIBA 01/2021
1	PropionatesIBA 11/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 11/2020
1	Food Additives (Food Additive)IBA 11/2020
1	Antidepressive Agents (Antidepressants)IBA 11/2020
1	Sirolimus (Rapamycin)FDA Link 10/2020
1	TOR Serine-Threonine KinasesIBA 10/2020
1	Neoplasm Antigens (Tumor Antigens)IBA 10/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	olaparibIBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	ferric oxide (iron oxide)IBA 01/2020
1	Circular RNAIBA 01/2020
1	SuspensionsIBA 01/2020
1	kushenIBA 08/2019
1	InterleukinsIBA 08/2019
1	AminoglycosidesIBA 09/2018
1	Neomycin FDA LinkGeneric 09/2018

Therapy/Procedure

9	Therapeutics 01/2021 - 05/2006
6	Immunotherapy 07/2021 - 05/2014
2	Transplantation 01/2022 - 01/2016
2	Drug Therapy (Chemotherapy) 01/2020 - 01/2017
1	Radiotherapy 01/2022
1	Brachytherapy 08/2019
1	Oral Administration 02/2018